Differences in the biologic activity of 2 novel MEK inhibitors revealed by 18F-FDG PET: analysis of imaging data from 2 phase I trials.

Differences in the biologic activity of 2 novel MEK inhibitors revealed by 18F-FDG PET: analysis of imaging data from 2 phase I trials.

UNLABELLED: Two mitogen-activated protein kinase kinase (MAPK2, also known as MEK) inhibitors were assessed with (18)F-FDG PET in separate phase I clinical studies, clearly illustrating the potential of metabolic imaging for dose, dosing regimen, and compound selection in early-phase trials and uti...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Kraeber-Bodéré, F, Carlier, T, Naegelen, V, Shochat, E, Lumbroso, J, Trampal, C, Nagarajah, J, Chua, S, Hugonnet, F, Stokkel, M, Gleeson, F, Tessier, J
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2012

Παρόμοια τεκμήρια

Interest of FDG-PET in the Management of Mantle Cell Lymphoma
ανά: Clément Bailly, κ.ά.
Έκδοση: (2019-04-01)

QUANTITATIVE EVALUATION OF THERAPEUTIC RESPONSE BY FDG PET-CT IN METASTATIC BREAST CANCER
ανά: Dorothée eGOULON, κ.ά.
Έκδοση: (2016-05-01)

Phase I dose-escalation study of the safety, pharmacokinetics, and pharmacodynamics of the MEK inhibitor RO4987655 (CH4987655) in patients with advanced solid tumors.
ανά: Leijen, S, κ.ά.
Έκδοση: (2012)

18-F FDG-PET in the staging of lymphocyte-predominant Hodgkin’s disease
ανά: Catherine Ansquer, κ.ά.
Έκδοση: (2008-01-01)

Prognostic value and clinical impact of 18FDG-PET in the management of children with Burkitt lymphoma after induction chemotherapy.
ανά: clement eBailly, κ.ά.
Έκδοση: (2014-12-01)

The role of 18F-FDG PET/CT in the evaluation of oesophageal carcinoma.
ανά: Chowdhury, F, κ.ά.
Έκδοση: (2008)

18F-FDG PET/CT of cervical carcinoma.
ανά: Patel, C, κ.ά.
Έκδοση: (2011)

DCE-MRI to distinguish all monoclonal plasma cell disease stages and correlation with diffusion-weighted MRI/PET-based biomarkers in a hybrid simultaneous whole body-2-[18F]FDG-PET/MRI imaging approach
ανά: Bastien Jamet, κ.ά.
Έκδοση: (2024-07-01)

Prognostic value of FDG-PET indices for the assessment of histological response to neoadjuvant chemotherapy and outcome in pediatric patients with Ewing sarcoma and osteosarcoma.
ανά: Clement Bailly, κ.ά.
Έκδοση: (2017-01-01)

Assessment of lymph nodes and prostate status using early dynamic curves with 18F-choline PET/CT in prostate cancer
ανά: Cédric eMathieu, κ.ά.
Έκδοση: (2015-09-01)

18FDG PET in lymphoma
ανά: Goldsmith Stanley J.
Έκδοση: (2012-01-01)

Investigation of FDG-PET/CT imaging to guide biopsies in the detection of histological transformation of indolent lymphoma
ανά: Caroline Bodet-Milin, κ.ά.
Έκδοση: (2008-03-01)

CLINICAL AND SURVIVAL IMPACT OF FDG PET IN PATIENTS WITH SUSPICION OF RECURRENT OVARIAN CANCER: A 6-YEAR FOLLOW-UP
ανά: Daniela eRusu, κ.ά.
Έκδοση: (2015-07-01)

Interest of Pet Imaging in Multiple Myeloma
ανά: Bastien Jamet, κ.ά.
Έκδοση: (2019-04-01)

Performance of baseline FDG-PET/CT radiomics for prediction of bone marrow minimal residual disease status in the LyMa-101 trial
ανά: Caroline Bodet-Milin, κ.ά.
Έκδοση: (2023-10-01)

Specific features to differentiate Giant cell arteritis aortitis from aortic atheroma using FDG-PET/CT
ανά: Olivier Espitia, κ.ά.
Έκδοση: (2021-08-01)

Sarcoid-like reaction to malignancy on whole-body integrated (18)F-FDG PET/CT: prevalence and disease pattern.
ανά: Chowdhury, F, κ.ά.
Έκδοση: (2009)

Prognostic value of FDG-PET in patients with mantle cell lymphoma: results from the LyMa-PET Project
ανά: Clément Bailly, κ.ά.
Έκδοση: (2020-01-01)

Myocarditis on 18FDG-PET imaging
ανά: Nourhan Chaaban, MD, κ.ά.
Έκδοση: (2022-06-01)

Applications of 18(F) FDG PET/CT in oncology
ανά: Ahmad Saad, Fathinul Fikri, κ.ά.
Έκδοση: (2015)

Re: Sarcoid-like reaction to malignancy on whole-body integrated (18)F-FDG PET/CT: prevalence and disease pattern-a reply
ανά: Chowdhury, F, κ.ά.
Έκδοση: (2010)

Revisiting the Robustness of PET-Based Textural Features in the Context of Multi-Centric Trials.
ανά: Clément Bailly, κ.ά.
Έκδοση: (2016-01-01)

The 18F-FDG PET scan in oncology
ανά: T Thientunyakit
Έκδοση: (2007-12-01)

A guideline proposal for mice preparation and care in 18F-FDG PET imaging
ανά: F. M. Ribeiro, κ.ά.
Έκδοση: (2022-08-01)

18F-FDG PET/MRI and 18F-FDG PET/CT for the Management of Gynecological Malignancies: A Comprehensive Review of the Literature
ανά: Leila Allahqoli, κ.ά.
Έκδοση: (2023-10-01)

Incidental findings on 18-FDG PET–CT in head and neck cancer. A retrospective case-control study of incidental findings on 18-FDG PET–CT in patients with head and neck cancer
ανά: Casselden, E, κ.ά.
Έκδοση: (2018)

18FDG-PET and large vessel vasculitis: preliminary data on 25 patients
ανά: L. Feggi, κ.ά.
Έκδοση: (2011-09-01)

2-deoxy-2-[18]fluoro-D-glucose PET/CT (18FDG PET/CT) may not be a viable biomarker in Pompe disease
ανά: U. Plöckinger, κ.ά.
Έκδοση: (2018-03-01)

Scar sarcoidosis on 18F-FDG PET/CT
ανά: Saurabh Arora, κ.ά.
Έκδοση: (2019-06-01)

Osteomyelitis detected by 18F-FDG PET-CT
ανά: Alberto Martinez-Lorca, κ.ά.
Έκδοση: (2024-05-01)

Semiquantitative 2-[18F]FDG PET/CT-based parameters role in lymphoma
ανά: Domenico Albano, κ.ά.
Έκδοση: (2024-12-01)

Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence
ανά: Piva R, κ.ά.
Έκδοση: (2017-07-01)

Total metabolic tumor volume on 18F-FDG PET/CT is a game-changer for patients with metastatic lung cancer treated with immunotherapy
ανά: Nicolas Martin, κ.ά.
Έκδοση: (2024-04-01)

FDG-positron-emission tomography for staging and therapeutic assessment in patients with plasmacytoma
ανά: Pierre-Yves Salaun, κ.ά.
Έκδοση: (2008-08-01)

Properties of S. aureus spondylodiscitis in CT and F18-FDG-PET/CT
ανά: J. Hockmann, κ.ά.
Έκδοση: (2024-01-01)

The Use of 18F-FDG-PET/CT for Diagnosis and Treatment Monitoring of Inflammatory and Infectious Diseases
ανά: Andor W. J. M. Glaudemans, κ.ά.
Έκδοση: (2013-01-01)

Is integrated 18F-FDG PET/MRI superior to 18F-FDG PET/CT in the differentiation of incidental tracer uptake in the head and neck area?
ανά: Benedikt Michael Schaarschmidt, κ.ά.
Έκδοση: (2017-03-01)

Diagnostic performance of prospective same-day 18F-FDG PET/MRI and 18F-FDG PET/CT in the staging and response assessment of lymphoma
ανά: Vijay Mistry, κ.ά.
Έκδοση: (2023-01-01)

Metástasis musculares no sospechadas detectadas con 18F-FDG PET/TC
ανά: J. San Román, κ.ά.
Έκδοση: (2017-01-01)

The systemic impact of different COVID-19 vaccines in 2-[18F] FDG-PET/CT
ανά: Tina Nazerani-Zemann, κ.ά.
Έκδοση: (2023-12-01)