Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

The SARS-CoV-2 virus is more transmissible than previous coronaviruses and causes a more serious illness than influenza. The SARS-CoV-2 receptor binding domain (RBD) of the spike protein binds to the human angiotensin-converting enzyme 2 (ACE2) receptor as a prelude to viral entry into the cell. Usi...

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Detalhes bibliográficos
Main Authors:	Huo, J, Le Bas, A, Ruza, RR, Duyvesten, HME, Mikolajek, H, Malinauskas, T, Tan, TK, Rijal, P, Dumoux, M, Ward, PN, Ren, J, Zhou, D, Harrison, PJ, Weckener, M, Clare, DK, Vogirala, VK, Radecke, J, Moynié, L, Zhao, Y, Gilbert-Jaramillo, J, Knight, ML, Tree, JA, Buttigieg, KR, Coombes, N, Elmore, MJ, Carroll, MW, Carrique, L, Shah, PNM, James, W, Townsend, AR, Stuart, DI, Owens, RJ, Naismith, JH
Formato:	Journal article
Idioma:	English
Publicado em:	Springer Nature 2020

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

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