The transcriptional effects of thermal injury and cooling on human skin and implications for wound healing
Cooling has a key role in burns first aid, but no clear mechanism. We have developed an ethically-approved, validated in vivo human model for cooling of partial-thickness burns utilising bilateral areas of abdominal skin discarded during DIEP surgery. Aims To create cooled and uncooled burns and con...
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| Format: | Conference item |
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Wiley
2018
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| _version_ | 1826271271175847936 |
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| author | Wright, H Tyler, M Harris, A Furniss, D |
| author_facet | Wright, H Tyler, M Harris, A Furniss, D |
| author_sort | Wright, H |
| collection | OXFORD |
| description | Cooling has a key role in burns first aid, but no clear mechanism. We have developed an ethically-approved, validated in vivo human model for cooling of partial-thickness burns utilising bilateral areas of abdominal skin discarded during DIEP surgery. Aims To create cooled and uncooled burns and controls in volunteers, and sequence their RNA for transcriptional changes caused by burning and cooling. |
| first_indexed | 2024-03-06T21:54:02Z |
| format | Conference item |
| id | oxford-uuid:4c4810cc-cf4e-4271-9f64-e34ae0b4bb25 |
| institution | University of Oxford |
| last_indexed | 2024-03-06T21:54:02Z |
| publishDate | 2018 |
| publisher | Wiley |
| record_format | dspace |
| spelling | oxford-uuid:4c4810cc-cf4e-4271-9f64-e34ae0b4bb252022-03-26T15:48:34ZThe transcriptional effects of thermal injury and cooling on human skin and implications for wound healingConference itemhttp://purl.org/coar/resource_type/c_5794uuid:4c4810cc-cf4e-4271-9f64-e34ae0b4bb25Symplectic Elements at OxfordWiley2018Wright, HTyler, MHarris, AFurniss, DCooling has a key role in burns first aid, but no clear mechanism. We have developed an ethically-approved, validated in vivo human model for cooling of partial-thickness burns utilising bilateral areas of abdominal skin discarded during DIEP surgery. Aims To create cooled and uncooled burns and controls in volunteers, and sequence their RNA for transcriptional changes caused by burning and cooling. |
| spellingShingle | Wright, H Tyler, M Harris, A Furniss, D The transcriptional effects of thermal injury and cooling on human skin and implications for wound healing |
| title | The transcriptional effects of thermal injury and cooling on human skin and implications for wound healing |
| title_full | The transcriptional effects of thermal injury and cooling on human skin and implications for wound healing |
| title_fullStr | The transcriptional effects of thermal injury and cooling on human skin and implications for wound healing |
| title_full_unstemmed | The transcriptional effects of thermal injury and cooling on human skin and implications for wound healing |
| title_short | The transcriptional effects of thermal injury and cooling on human skin and implications for wound healing |
| title_sort | transcriptional effects of thermal injury and cooling on human skin and implications for wound healing |
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