Lactic acidosis and hypoglycaemia in children with severe malaria: pathophysiological and prognostic significance.
Serial clinical and metabolic changes were monitored in 115 Gambian children (1.5-12 years old) with severe malaria. Fifty-three children (46%) had cerebral malaria (coma score < or = 2) and 21 (18%) died. Admission geometric mean venous blood lactate concentrations were almost twice as high...
Main Authors: | Krishna, S, Waller, D, ter Kuile, F, Kwiatkowski, D, Crawley, J, Craddock, C, Nosten, F, Chapman, D, Brewster, D, Holloway, P |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1994
|
Similar Items
-
The pathophysiologic and prognostic significance of acidosis in severe adult malaria.
by: Day, N, et al.
Published: (2000) -
Plasmodium berghei: lactic acidosis and hypoglycaemia in a rodent model of severe malaria; effects of glucose, quinine, and dichloroacetate.
by: Holloway, P, et al.
Published: (1991) -
Plasmodium berghei infection: dichloroacetate improves survival in rats with lactic acidosis.
by: Holloway, P, et al.
Published: (1995) -
Dichloroacetate for lactic acidosis in severe malaria: a pharmacokinetic and pharmacodynamic assessment.
by: Krishna, S, et al.
Published: (1994) -
Clinical features and outcome of severe malaria in Gambian children.
by: Waller, D, et al.
Published: (1995)