Chronic activation of γ2 AMPK induces obesity and reduces β cell function

Chronic activation of γ2 AMPK induces obesity and reduces β cell function

Despite significant advances in our understanding of the biology determining systemic energy homeostasis, the treatment of obesity remains a medical challenge. Activation of AMP-activated protein kinase (AMPK) has been proposed as an attractive strategy for the treatment of obesity and its complicat...

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Main Authors: Yavari, A, Stocker, C, Ghaffari, S, Wargent, E, Steeples, V, Czibik, G, Pinter, K, Bellahcene, M, Oliver, P, Stockenhuber, A, Nguyen, C, Lazdam, M, Kyriakou, T, Parnis, J, Sarma, D, Katritsis, G, Wortmann, D, Harper, A, Brown, L, Peirson, S, Redwood, C, Watkins, H, Ashrafian, H
Format: Journal article
Published: Cell Press 2016

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