Chronic activation of γ2 AMPK induces obesity and reduces β cell function
Despite significant advances in our understanding of the biology determining systemic energy homeostasis, the treatment of obesity remains a medical challenge. Activation of AMP-activated protein kinase (AMPK) has been proposed as an attractive strategy for the treatment of obesity and its complicat...
Glavni autori: | Yavari, A, Stocker, C, Ghaffari, S, Wargent, E, Steeples, V, Czibik, G, Pinter, K, Bellahcene, M, Oliver, P, Stockenhuber, A, Nguyen, C, Lazdam, M, Kyriakou, T, Parnis, J, Sarma, D, Katritsis, G, Wortmann, D, Harper, A, Brown, L, Peirson, S, Redwood, C, Watkins, H, Ashrafian, H |
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Format: | Journal article |
Izdano: |
Cell Press
2016
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