Structural basis for LMO2-driven recruitment of the SCL:E47bHLH heterodimer to hematopoietic-specific transcriptional targets.

Cell fate is governed by combinatorial actions of transcriptional regulators assembling into multiprotein complexes. However, the molecular details of how these complexes form are poorly understood. One such complex, which contains the basic-helix-loop-helix heterodimer SCL:E47 and bridging proteins...

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Bibliografiska uppgifter
Huvudupphovsmän: El Omari, K, Hoosdally, S, Tuladhar, K, Karia, D, Hall-Ponselé, E, Platonova, O, Vyas, P, Patient, R, Porcher, C, Mancini, E
Materialtyp: Journal article
Språk:English
Publicerad: 2013