Desferrioxamine elevates pulmonary vascular resistance in humans: potential for involvement of HIF-1.

Desferrioxamine elevates pulmonary vascular resistance in humans: potential for involvement of HIF-1.

Hypoxia-inducible factor (HIF)-1 is stabilized by hypoxia and iron chelation. We hypothesized that HIF-1 might be involved in pulmonary vascular regulation and that infusion of desferrioxamine over 8 h would consequently mimic hypoxia and elevate pulmonary vascular resistance. In study A, we charact...

書誌詳細
主要な著者:	Balanos, G, Dorrington, K, Robbins, P
フォーマット:	Journal article
言語:	English
出版事項:	2002

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