Anti-coreceptor antibodies profoundly affect staining with peptide-MHC class I and class II tetramers.

Anti-coreceptor antibodies profoundly affect staining with peptide-MHC class I and class II tetramers.

The T cell coreceptors CD8 and CD4 bind to invariable regions of peptide-MHC class I (pMHCI) and class II (pMHCII) molecules, respectively, and facilitate antigen recognition by a number of mechanisms. It is established that some antibodies (Ab) specific for the CD8 molecule, which stabilizes TCR/pM...

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Bibliographic Details
Main Authors:	Wooldridge, L, Scriba, T, Milicic, A, Laugel, B, Gostick, E, Price, D, Phillips, R, Sewell, A
Format:	Journal article
Language:	English
Published:	2006

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