Selective hydrolysis of triple-helical substrates by matrix metalloproteinase-2 and -9.

Selective hydrolysis of triple-helical substrates by matrix metalloproteinase-2 and -9.

The role of proteases in the tumor cell invasion process is multifaceted. Members of the matrix metalloproteinase (MMP) family have been implicated in primary and metastatic tumor growth, angiogenesis, and degradation of extracellular matrix (ECM) components. Differentiating between the up-regulatio...

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Bibliographic Details
Main Authors:	Lauer-Fields, J, Sritharan, T, Stack, MS, Nagase, H, Fields, G
Format:	Journal article
Language:	English
Published:	2003

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