The kinetic-segregation model: TCR triggering and beyond.

How the T cell receptor engages antigen is known, but not how that 'triggers' intracellular signaling. The first direct support for a mechanism based on the spatial reorganization of signaling proteins, proposed 10 years ago and referred to as the 'kinetic-segregation' model, is...

Description complète

Détails bibliographiques
Auteurs principaux: Davis, S, Van Der Merwe, P
Format: Journal article
Langue:English
Publié: 2006