H-NS-mediated repression of CRISPR-based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO.

The recently discovered prokaryotic CRISPR/Cas defence system provides immunity against viral infections and plasmid conjugation. It has been demonstrated that in Escherichia coli transcription of the Cascade genes (casABCDE) and to some extent the CRISPR array is repressed by heat-stable nucleoid-s...

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מידע ביבליוגרפי
Main Authors: Westra, E, Pul, U, Heidrich, N, Jore, M, Lundgren, M, Stratmann, T, Wurm, R, Raine, A, Mescher, M, Van Heereveld, L, Mastop, M, Wagner, E, Schnetz, K, Van Der Oost, J, Wagner, R, Brouns, S
פורמט: Journal article
שפה:English
יצא לאור: 2010