γδ T cells support pancreatic oncogenesis by restraining αβ T cell activation

γδ T cells support pancreatic oncogenesis by restraining αβ T cell activation

Inflammation is paramount in pancreatic oncogenesis. We identified a uniquely activated γδT cell population, which constituted ~40% of tumor-infiltrating T cells in human pancreatic ductal adenocarcinoma (PDA). Recruitment and activation of γδT cells was contingent on diverse chemokine signals. Dele...

Podrobná bibliografie
Hlavní autoři:	Daley, D, Zambirinis, C, Seifert, L, Akkad, N, Mohan, N, Werba, G, Barilla, R, Torres-Hernandez, A, Hundeyin, M, Mani, V, Avanzi, A, Tippens, D, Narayanan, R, Jang, J, Newman, E, Pillarisetty, V, Dustin, M, Bar-Sagi, D, Hajdu, C, Miller, G
Médium:	Journal article
Jazyk:	English
Vydáno:	Elsevier 2016

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