Common polymorphisms in the PKP3-SIGIRR-TMEM16J gene region are associated with susceptibility to tuberculosis.
BACKGROUND: Tuberculosis has been associated with genetic variation in host immunity. We hypothesized that single-nucleotide polymorphisms (SNPs) in SIGIRR, a negative regulator of Toll-like receptor/IL-1R signaling, are associated with susceptibility to tuberculosis. METHODS: We used a case-populat...
Main Authors: | Horne, D, Randhawa, A, Chau, T, Bang, N, Yen, N, Farrar, J, Dunstan, S, Hawn, T |
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Format: | Journal article |
Language: | English |
Published: |
2012
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