Assessment of tropism and effectiveness of new primate-derived hybrid recombinant AAV serotypes in the mouse and primate retina
Adeno-associated viral vectors (AAV) have been shown to be safe in the treatment of retinal degenerations in clinical trials. Thus, improving the efficiency of viral gene delivery has become increasingly important to increase the success of clinical trials. In this study, structural domains of diffe...
Main Authors: | Charbel Issa, P, Silva, D, Lipinski, D, Singh, MS, Mouravlev, A, You, Q, Barnard, A, Hankins, M, During, M, Maclaren, R |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2013
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