Variability in high−throughput ion channel screening data and consequences for cardiac safety assessment

Variability in high−throughput ion channel screening data and consequences for cardiac safety assessment

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Introduction: unwanted drug interactions with ionic currents in the heart can lead to an increased pro-arrhythmic risk to patients in the clinic. It is therefore a priority for pharmaceutical safety pharmacology teams to detect block of cardiac ion channels, and new technologies have enabled the dev...

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Những tác giả chính:	Elkins, R, Davies, M, Brough, S, Gavaghan, D, Cui, Y, Abi−Gerges, N, Mirams, G
Định dạng:	Journal article
Được phát hành:	2013

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