[Effect of mutation Arg9lGly on the thermal stability of beta-tropomyosin]

The mutation Arg91Gly (R91G) in beta-tropomyosin (beta-TM) is known to cause distal arthrogryposis, a severe congenital disorder of muscle tissues. To elucidate how this mutation affects the structural properties of beta-TM, the thermal unfolding of beta-TM carrying mutation Arg91Gly was compared wi...

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Detalles Bibliográficos
Autores principales: Nevzorov, I, Redwood, C, Levitskiĭ, D
Formato: Journal article
Lenguaje:Russian
Publicado: 2008