High-throughput expression and purification of human solute carriers for structural and biochemical studies

High-throughput expression and purification of human solute carriers for structural and biochemical studies

Solute carriers (SLCs) are membrane transporters that import and export a range of endogenous and exogenous substrates, including ions, nutrients, metabolites, neurotransmitters, and pharmaceuticals. Despite having emerged as attractive therapeutic targets and markers of disease, this group of prote...

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Bibliographic Details
Main Authors: Raturi, S, Li, H, Chang, Y-N, Scacioc, A, Bohstedt, T, Fernandez-Cid, A, Evans, A, Abrusci, P, Balakrishnan, A, Pascoa, TC, He, D, Chi, G, Kaur Singh, N, Ye, M, Li, A, Shrestha, L, Wang, D, Williams, EP, Burgess-Brown, NA, Dürr, KL, Puetter, V, Ingles-Prieto, A, Sauer, DB
Format: Journal article
Language:English
Published: MyJove Corporation 2023

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