Molecular characterisation of ASXL1-mutant clonal haematopoiesis
Adult stem cells accumulate somatic mutations throughout life as a result of failure to repair DNA damage. If a somatic mutation confers a fitness advantage upon the stem cell, the resulting clone can expand to be over-represented in that tissue. In the haematopoietic system, this process is known a...
| المؤلف الرئيسي: | |
|---|---|
| مؤلفون آخرون: | |
| التنسيق: | أطروحة |
| اللغة: | English |
| منشور في: |
2024
|