Deep-brain stimulation

Deep-brain stimulation (DBS) is a clinical intervention that has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders. The resulting direct causal manipulation of both local and distributed brain networks is not only clinically helpful but can a...

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Bibliografiske detaljer
Main Authors: Kringelbach, M, Owen, S, Aziz, T
Format: Journal article
Sprog:English
Udgivet: 2007
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author Kringelbach, M
Owen, S
Aziz, T
author_facet Kringelbach, M
Owen, S
Aziz, T
author_sort Kringelbach, M
collection OXFORD
description Deep-brain stimulation (DBS) is a clinical intervention that has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders. The resulting direct causal manipulation of both local and distributed brain networks is not only clinically helpful but can also help to provide novel fundamental insights into brain function. In particular, DBS can be used in conjunction with methods such as local field potentials and magnetoencephalography to map the underlying mechanisms of normal and abnormal oscillatory synchronization in the brain. The precise mechanisms of action for DBS remain uncertain but here we present an overview of the clinical efficacy of DBS, its neural mechanisms and potential future applications. © 2007 Future Medicine Ltd.
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spelling oxford-uuid:4d299704-f11a-4d05-bcfd-a0b8cd709bc62022-03-26T15:53:51ZDeep-brain stimulationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4d299704-f11a-4d05-bcfd-a0b8cd709bc6EnglishSymplectic Elements at Oxford2007Kringelbach, MOwen, SAziz, TDeep-brain stimulation (DBS) is a clinical intervention that has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders. The resulting direct causal manipulation of both local and distributed brain networks is not only clinically helpful but can also help to provide novel fundamental insights into brain function. In particular, DBS can be used in conjunction with methods such as local field potentials and magnetoencephalography to map the underlying mechanisms of normal and abnormal oscillatory synchronization in the brain. The precise mechanisms of action for DBS remain uncertain but here we present an overview of the clinical efficacy of DBS, its neural mechanisms and potential future applications. © 2007 Future Medicine Ltd.
spellingShingle Kringelbach, M
Owen, S
Aziz, T
Deep-brain stimulation
title Deep-brain stimulation
title_full Deep-brain stimulation
title_fullStr Deep-brain stimulation
title_full_unstemmed Deep-brain stimulation
title_short Deep-brain stimulation
title_sort deep brain stimulation
work_keys_str_mv AT kringelbachm deepbrainstimulation
AT owens deepbrainstimulation
AT azizt deepbrainstimulation