Low affinity of cell surface lymphocyte function-associated antigen-1 (LFA-1) generates selectivity for cell-cell interactions.

We examined binding of soluble intercellular adhesion molecule-1 (ICAM-1) dimers and a range of ICAM-1-coated particles to activated T cells. Lymphocyte function-associated antigen-1 (LFA-1) on the surface of activated T cells did not bind soluble ICAM-1 dimers with high affinity. In contrast, activ...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Ganpule, G, Knorr, R, Miller, J, Carron, C, Dustin, M
פורמט: Journal article
שפה:English
יצא לאור: 1997