Recapitulation of Werner syndrome sensitivity to camptothecin by limited knockdown of the WRN helicase/exonuclease

Recapitulation of Werner syndrome sensitivity to camptothecin by limited knockdown of the WRN helicase/exonuclease

Diğer sürümleri göster (1)

WRN is a RecQ helicase with an associated exonuclease activity important in DNA metabolism, including DNA replication, repair and recombination. In humans, deficiencies in WRN function cause the segmental progeroid Werner syndrome (WS), in which patients show premature onset of many hallmarks of nor...

Detaylı Bibliyografya
Asıl Yazarlar:	Bird, J, Jennert-Burston, K, Bachler, M, Mason, P, Lowe, J, Heo, S, Campisi, J, Faragher, R, Cox, L
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2012

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