DNA repair pathways as targets for cancer therapy.
DNA repair pathways can enable tumour cells to survive DNA damage that is induced by chemotherapeutic treatments; therefore, inhibitors of specific DNA repair pathways might prove efficacious when used in combination with DNA-damaging chemotherapeutic drugs. In addition, alterations in DNA repair pa...
Main Authors: | Helleday, T, Petermann, E, Lundin, C, Hodgson, B, Sharma, R |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
2008
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