Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation?

CONTEXT: The etiology of idiopathic intracranial hypertension (IIH) is unknown. We hypothesized that obesity and elevated intracranial pressure may be linked through increased 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) activity. OBJECTIVE: The aim was to characterize 11β-HSD1 in human cerebr...

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Main Authors: Sinclair, A, Walker, E, Burdon, M, van Beek, A, Kema, I, Hughes, B, Murray, P, Nightingale, P, Stewart, P, Rauz, S, Tomlinson, J
格式: Journal article
语言:English
出版: 2010

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