A neuronal circuit driven by GLP-1 in the olfactory bulb regulates insulin secretion

Glucagon-like peptide 1 (GLP-1) stimulates insulin secretion and holds significant pharmacological potential. Nevertheless, the regulation of energy homeostasis by centrally-produced GLP-1 remains partially understood. Preproglucagon cells, known to release GLP-1, are found in the olfactory bulb (OB...

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Bibliographic Details
Main Authors: Montaner, M, Denom, J, Simon, V, Jiang, W, Holt, MK, Brierley, DI, Rouch, C, Foppen, E, Kassis, N, Jarriault, D, Khan, D, Eygret, L, Mifsud, F, Hodson, DJ, Broichhagen, J, Van Oudenhove, L, Fioramonti, X, Gault, V, Cota, D, Reimann, F, Gribble, FM, Migrenne-Li, S, Trapp, S, Gurden, H
Format: Journal article
Language:English
Published: Nature Research 2024