Effect of ribavirin and interferon on the outcome of critically ill patients with mers

Interferon and ribavirin have been used in the treatment of the Middle East Respiratory Syndrome (MERS), but the efficacy of this therapy remains uncertain. Existing data are limited by the lack of adjustment to time-dependent covariates at the time of initiation of therapy. This study objective is...

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Bibliographic Details
Main Authors: Arabi, YM, Shalhoub, S, Omari, A, Mandourah, Y, Al-Hameed, F, Sindi, A, Alraddadi, B, Motairi, A, Khatib, K, Mommin, AA, Qushmaq, IA, Mady, A, Solaiman, O, Aithan, A, Balkhy, HH, Al-Raddadi, R, Rajab, A, Mekhlafi, GA, Harthy, A, Kharaba, A, Al-Jabbary, A, Pinto, R, Sadat, M, Mutairi, H, Qasim, E, Jose, J, Deeb, AM, Merson, L, Hayden, FG, Fowler, R, Aldawood, AS
Format: Conference item
Published: American Thoracic Society 2017
Description
Summary:Interferon and ribavirin have been used in the treatment of the Middle East Respiratory Syndrome (MERS), but the efficacy of this therapy remains uncertain. Existing data are limited by the lack of adjustment to time-dependent covariates at the time of initiation of therapy. This study objective is to examine the association of ribavirin/interferon in critically ill MERS patients using marginal structural models.