Solution and crystallographic structures of the central region of the phosphoprotein from human metapneumovirus

Human metapneumovirus (HMPV) of the family Paramyxoviridae is a major cause of respiratory illness worldwide. Phosphoproteins (P) from Paramyxoviridae are essential co-factors of the viral RNA polymerase that form tetramers and possess long intrinsically disordered regions (IDRs). We located the cen...

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Hlavní autoři: Leyrat, C, Renner, M, Harlos, K, Grimes, J
Médium: Journal article
Jazyk:English
Vydáno: Public Library of Science 2013