Targeted killing of colorectal cancer cell lines by a humanised IgG1 monoclonal antibody that binds to membrane-bound carcinoembryonic antigen.

Targeted killing of colorectal cancer cell lines by a humanised IgG1 monoclonal antibody that binds to membrane-bound carcinoembryonic antigen.

The distribution of carcinoembryonic antigen (CEA) in colorectal cancer (CRC) differs from that in normal colorectal tissue, being found on all borders of the cell membrane and hence enabling access to intravenous antibody, making CEA a good target for antibody-based therapy. The distinctive anti-CE...

Podrobná bibliografie
Hlavní autoři:	Conaghan, P, Ashraf, S, Tytherleigh, M, Wilding, J, Tchilian, E, Bicknell, D, Mortensen, N, Bodmer, W
Médium:	Journal article
Jazyk:	English
Vydáno:	2008

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