Short-term memory advantage for brief durations in human APOE ε4 carriers

The Apolipoprotein-E (APOE) ε4 gene allele, the highest known genetic risk factor for Alzheimer’s disease, has paradoxically been well preserved in the human population. One possible explanation offered by evolutionary biology for survival of deleterious genes is antagonistic pleiotropy. This theory...

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Bibliographic Details
Main Authors: Zokaei, N, Grogan, J, Fallon, SJ, Slavkova, E, Hadida, J, Manohar, S, De Ozorio Nobre, A, Husain, M
Format: Journal article
Language:English
Published: Nature Research 2020