Tracking early mammalian organogenesis – prediction and validation of differentiation trajectories at whole organism scale
Early organogenesis represents a key step in animal development, during which pluripotent cells diversify to initiate organ formation. Here, we sampled 300,000 single-cell transcriptomes from mouse embryos between E8.5 and E9.5 in 6-h intervals and combined this new dataset with our previous atlas (...
Main Authors: | Imaz-Rosshandler, I, Rode, C, Guibentif, C, Harland, LTG, Ton, M-LN, Dhapola, P, Keitley, D, Argelaguet, R, Calero-Nieto, FJ, Nichols, J, Marioni, JC, de Bruijn, MFTR, Göttgens, B |
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Format: | Journal article |
Language: | English |
Published: |
The Company of Biologists
2024
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