YAP-DKK1 axis restricts regeneration to the isthmus of the human gastric glands

YAP-DKK1 axis restricts regeneration to the isthmus of the human gastric glands

<p>In the gastrointestinal tract, tissue regeneration relies on stem cells localised within specific niches. The factors determining this spatial restriction remain unknown. Coordinated activation of signalling pathways is essential during organogenesis and extends to adult tissue for the main...

Bibliografske podrobnosti
Glavni avtor:	Zagami, C
Drugi avtorji:	Boccellato, F
Format:	Thesis
Jezik:	English
Izdano:	2024
Teme:	This thesis postulates that YAP-DKK1 interaction restricts regenerative cellular activity to the isthmus of the stomach gastric gland, by inhibiting Wnt/β-catenin signalling pathway.

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