Large-scale evidence that the cardiotoxicity of smoking is not significantly modified by the apolipoprotein E epsilon2/epsilon3/epsilon4 genotype.

Results from two small studies, involving a total of only 174 cases, have suggested that the increased risk of coronary heart disease conferred by cigarette smoking is substantially affected by genotype at the apolipoprotein E (APOE) epsilon2/epsilon3/epsilon4 polymorphism. We have established APOE...

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Autors principals: Keavney, B, Parish, S, Palmer, A, Clark, S, Youngman, L, Danesh, J, McKenzie, C, Delépine, M, Lathrop, M, Peto, R, Collins, R
Format: Journal article
Idioma:English
Publicat: 2003