Gray and white matter degeneration revealed by diffusion in an Alzheimer mouse model.

In patients with Alzheimer's disease (AD) the severity of white matter degeneration correlates with the clinical symptoms of the disease. In this study, we performed diffusion-tensor magnetic resonance imaging at ultra-high field in a mouse model for AD (APP(swe)/PS1(dE9)) in combination with a...

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Main Authors: Zerbi, V, Kleinnijenhuis, M, Fang, X, Jansen, D, Veltien, A, Van Asten, J, Timmer, N, Dederen, P, Kiliaan, A, Heerschap, A
格式: Journal article
语言:English
出版: 2013