Role of depression in heart failure--choosing the right antidepressive treatment.
Major depression is a common feature of heart failure patients and possibly stems from their common biochemical background. Depression and heart failure co-morbidity has several clinical implications on the prognosis of these patients. Furthermore antidepressive drugs have known cardiovascular side...
| Hoofdauteurs: | , , , , , , , , , |
|---|---|
| Formaat: | Journal article |
| Taal: | English |
| Gepubliceerd in: |
2010
|
| _version_ | 1826271582484430848 |
|---|---|
| author | Tousoulis, D Antonopoulos, A Antoniades, C Saldari, C Stefanadi, E Siasos, G Stougianos, P Plastiras, A Korompelis, P Stefanadis, C |
| author_facet | Tousoulis, D Antonopoulos, A Antoniades, C Saldari, C Stefanadi, E Siasos, G Stougianos, P Plastiras, A Korompelis, P Stefanadis, C |
| author_sort | Tousoulis, D |
| collection | OXFORD |
| description | Major depression is a common feature of heart failure patients and possibly stems from their common biochemical background. Depression and heart failure co-morbidity has several clinical implications on the prognosis of these patients. Furthermore antidepressive drugs have known cardiovascular side effects, while their safety and efficacy in heart failure has not been fully elucidated yet. The right choice of antidepressive treatment in heart failure constitutes an issue of high importance as it can affect the clinical outcome of these patients. In this article we highlight the role of major depression in heart failure and demonstrate their common biochemical background. Moreover we review the acquired so far knowledge on the use of the various categories of antidepressants in heart failure by reference to the existing clinical studies on antidepressants efficacy and safety in heart failure. Even though certain conclusions cannot be drawn yet, evidence suggests that the use of selective serotonin reuptake inhibitors may have a beneficial effect on clinical outcome of heart failure patients. |
| first_indexed | 2024-03-06T21:58:55Z |
| format | Journal article |
| id | oxford-uuid:4debada3-9fa1-4e0e-a14f-cf38d61083fe |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:58:55Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | oxford-uuid:4debada3-9fa1-4e0e-a14f-cf38d61083fe2022-03-26T15:58:10ZRole of depression in heart failure--choosing the right antidepressive treatment.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4debada3-9fa1-4e0e-a14f-cf38d61083feEnglishSymplectic Elements at Oxford2010Tousoulis, DAntonopoulos, AAntoniades, CSaldari, CStefanadi, ESiasos, GStougianos, PPlastiras, AKorompelis, PStefanadis, CMajor depression is a common feature of heart failure patients and possibly stems from their common biochemical background. Depression and heart failure co-morbidity has several clinical implications on the prognosis of these patients. Furthermore antidepressive drugs have known cardiovascular side effects, while their safety and efficacy in heart failure has not been fully elucidated yet. The right choice of antidepressive treatment in heart failure constitutes an issue of high importance as it can affect the clinical outcome of these patients. In this article we highlight the role of major depression in heart failure and demonstrate their common biochemical background. Moreover we review the acquired so far knowledge on the use of the various categories of antidepressants in heart failure by reference to the existing clinical studies on antidepressants efficacy and safety in heart failure. Even though certain conclusions cannot be drawn yet, evidence suggests that the use of selective serotonin reuptake inhibitors may have a beneficial effect on clinical outcome of heart failure patients. |
| spellingShingle | Tousoulis, D Antonopoulos, A Antoniades, C Saldari, C Stefanadi, E Siasos, G Stougianos, P Plastiras, A Korompelis, P Stefanadis, C Role of depression in heart failure--choosing the right antidepressive treatment. |
| title | Role of depression in heart failure--choosing the right antidepressive treatment. |
| title_full | Role of depression in heart failure--choosing the right antidepressive treatment. |
| title_fullStr | Role of depression in heart failure--choosing the right antidepressive treatment. |
| title_full_unstemmed | Role of depression in heart failure--choosing the right antidepressive treatment. |
| title_short | Role of depression in heart failure--choosing the right antidepressive treatment. |
| title_sort | role of depression in heart failure choosing the right antidepressive treatment |
| work_keys_str_mv | AT tousoulisd roleofdepressioninheartfailurechoosingtherightantidepressivetreatment AT antonopoulosa roleofdepressioninheartfailurechoosingtherightantidepressivetreatment AT antoniadesc roleofdepressioninheartfailurechoosingtherightantidepressivetreatment AT saldaric roleofdepressioninheartfailurechoosingtherightantidepressivetreatment AT stefanadie roleofdepressioninheartfailurechoosingtherightantidepressivetreatment AT siasosg roleofdepressioninheartfailurechoosingtherightantidepressivetreatment AT stougianosp roleofdepressioninheartfailurechoosingtherightantidepressivetreatment AT plastirasa roleofdepressioninheartfailurechoosingtherightantidepressivetreatment AT korompelisp roleofdepressioninheartfailurechoosingtherightantidepressivetreatment AT stefanadisc roleofdepressioninheartfailurechoosingtherightantidepressivetreatment |