Graphite micropowder modified with 4-amino-2,6-diphenylphenol supported on basal plane pyrolytic graphite electrodes: Micro sensing platforms for the indirect electrochemical detection of Delta(9)-tetrahydrocannabinol in saliva
Graphite micropowder has been modified with 4-amino-2,6-diphenylphenol immobilized onto a basal plane pyrolytic graphite electrode and explored for the indirect electrochemical sensing of Δ9-tetrahydrocannabinol in artificial saliva. The protocol is based on the electrochemical formation of quinonei...
| Autores principales: | , , |
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| Formato: | Journal article |
| Lenguaje: | English |
| Publicado: |
2006
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| Sumario: | Graphite micropowder has been modified with 4-amino-2,6-diphenylphenol immobilized onto a basal plane pyrolytic graphite electrode and explored for the indirect electrochemical sensing of Δ9-tetrahydrocannabinol in artificial saliva. The protocol is based on the electrochemical formation of quinoneimine which specifically reacts with Δ9- tetrahydrocannabinol resulting in the loss of the quinoneimine which can be monitored via voltammetry. It is demonstrated that Δ9- tetrahydrocannabinol can be detected in artificial saliva over the micromolar range. Such a protocol may find application in screening for drug abuse. |
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