Graphite micropowder modified with 4-amino-2,6-diphenylphenol supported on basal plane pyrolytic graphite electrodes: Micro sensing platforms for the indirect electrochemical detection of Delta(9)-tetrahydrocannabinol in saliva
Graphite micropowder has been modified with 4-amino-2,6-diphenylphenol immobilized onto a basal plane pyrolytic graphite electrode and explored for the indirect electrochemical sensing of Δ9-tetrahydrocannabinol in artificial saliva. The protocol is based on the electrochemical formation of quinonei...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2006
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| _version_ | 1826271583094702080 |
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| author | Goodwin, A Banks, C Compton, R |
| author_facet | Goodwin, A Banks, C Compton, R |
| author_sort | Goodwin, A |
| collection | OXFORD |
| description | Graphite micropowder has been modified with 4-amino-2,6-diphenylphenol immobilized onto a basal plane pyrolytic graphite electrode and explored for the indirect electrochemical sensing of Δ9-tetrahydrocannabinol in artificial saliva. The protocol is based on the electrochemical formation of quinoneimine which specifically reacts with Δ9- tetrahydrocannabinol resulting in the loss of the quinoneimine which can be monitored via voltammetry. It is demonstrated that Δ9- tetrahydrocannabinol can be detected in artificial saliva over the micromolar range. Such a protocol may find application in screening for drug abuse. |
| first_indexed | 2024-03-06T21:58:56Z |
| format | Journal article |
| id | oxford-uuid:4dec6482-0f91-41e9-aba6-1ad7add73c80 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:58:56Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:4dec6482-0f91-41e9-aba6-1ad7add73c802022-03-26T15:58:11ZGraphite micropowder modified with 4-amino-2,6-diphenylphenol supported on basal plane pyrolytic graphite electrodes: Micro sensing platforms for the indirect electrochemical detection of Delta(9)-tetrahydrocannabinol in salivaJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4dec6482-0f91-41e9-aba6-1ad7add73c80EnglishSymplectic Elements at Oxford2006Goodwin, ABanks, CCompton, RGraphite micropowder has been modified with 4-amino-2,6-diphenylphenol immobilized onto a basal plane pyrolytic graphite electrode and explored for the indirect electrochemical sensing of Δ9-tetrahydrocannabinol in artificial saliva. The protocol is based on the electrochemical formation of quinoneimine which specifically reacts with Δ9- tetrahydrocannabinol resulting in the loss of the quinoneimine which can be monitored via voltammetry. It is demonstrated that Δ9- tetrahydrocannabinol can be detected in artificial saliva over the micromolar range. Such a protocol may find application in screening for drug abuse. |
| spellingShingle | Goodwin, A Banks, C Compton, R Graphite micropowder modified with 4-amino-2,6-diphenylphenol supported on basal plane pyrolytic graphite electrodes: Micro sensing platforms for the indirect electrochemical detection of Delta(9)-tetrahydrocannabinol in saliva |
| title | Graphite micropowder modified with 4-amino-2,6-diphenylphenol supported on basal plane pyrolytic graphite electrodes: Micro sensing platforms for the indirect electrochemical detection of Delta(9)-tetrahydrocannabinol in saliva |
| title_full | Graphite micropowder modified with 4-amino-2,6-diphenylphenol supported on basal plane pyrolytic graphite electrodes: Micro sensing platforms for the indirect electrochemical detection of Delta(9)-tetrahydrocannabinol in saliva |
| title_fullStr | Graphite micropowder modified with 4-amino-2,6-diphenylphenol supported on basal plane pyrolytic graphite electrodes: Micro sensing platforms for the indirect electrochemical detection of Delta(9)-tetrahydrocannabinol in saliva |
| title_full_unstemmed | Graphite micropowder modified with 4-amino-2,6-diphenylphenol supported on basal plane pyrolytic graphite electrodes: Micro sensing platforms for the indirect electrochemical detection of Delta(9)-tetrahydrocannabinol in saliva |
| title_short | Graphite micropowder modified with 4-amino-2,6-diphenylphenol supported on basal plane pyrolytic graphite electrodes: Micro sensing platforms for the indirect electrochemical detection of Delta(9)-tetrahydrocannabinol in saliva |
| title_sort | graphite micropowder modified with 4 amino 2 6 diphenylphenol supported on basal plane pyrolytic graphite electrodes micro sensing platforms for the indirect electrochemical detection of delta 9 tetrahydrocannabinol in saliva |
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