Anti-CD4-mediated selection of Treg in vitro - in vitro suppression does not predict in vivo capacity to prevent graft rejection.

Regulatory T cells (Treg) have been shown to play a role in the prevention of autoimmune diseases and transplant rejection. Based on an established protocol known to generate alloantigen reactive Treg in vivo, we have developed a strategy for the in vitro selection of Treg. Stimulation of unfraction...

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Váldodahkkit: Oliveira, V, Sawitzki, B, Chapman, S, Appelt, C, Gebuhr, I, Wieckiewicz, J, Long, E, Wood, K
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2008