SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation.

SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation.

Generally, F-box proteins are the substrate recognition subunits of SCF (Skp1-Cul1-F-box protein) ubiquitin ligase complexes, which mediate the timely proteolysis of important eukaryotic regulatory proteins. Mammalian genomes encode roughly 70 F-box proteins, but only a handful have established func...

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Dades bibliogràfiques
Autors principals:	D'Angiolella, V, Donato, V, Vijayakumar, S, Saraf, A, Florens, L, Washburn, M, Dynlacht, B, Pagano, M
Format:	Journal article
Idioma:	English
Publicat:	2010

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