Phosphorylated pVEGFR2/KDR receptor expression in uveal melanomas: relation with HIF2α and survival.
Hypoxia and its down-stream activated pathways are commonly involved in tumor progression. Genes involved in angiogenesis and glycolysis, i.e. vascular endothelial growth factor (VEGF) and lactase dehydrogenase A (LDHA), respectively, are transcriptionally controlled by the hypoxia inducible factors...
Huvudupphovsmän: | Giatromanolaki, A, Sivridis, E, Bechrakis, N, Willerding, G, St Charitoudis, G, Foerster, M, Gatter, K, Harris, A, Koukourakis, M |
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Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
2012
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