Phosphorylated pVEGFR2/KDR receptor expression in uveal melanomas: relation with HIF2α and survival.

Phosphorylated pVEGFR2/KDR receptor expression in uveal melanomas: relation with HIF2α and survival.

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Hypoxia and its down-stream activated pathways are commonly involved in tumor progression. Genes involved in angiogenesis and glycolysis, i.e. vascular endothelial growth factor (VEGF) and lactase dehydrogenase A (LDHA), respectively, are transcriptionally controlled by the hypoxia inducible factors...

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मुख्य लेखकों: Giatromanolaki, A, Sivridis, E, Bechrakis, N, Willerding, G, St Charitoudis, G, Foerster, M, Gatter, K, Harris, A, Koukourakis, M
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2012
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