THE TYPE III 8-10 REPEATS OF FIBRONECTIN INDUCE AGGRECANASE ACTIVITY VIA ALPHA5BETA1 INTEGRIN AND THE TYPE III 13-14 REPEATS ACT VIA TLR 4 RECEPTORS

THE TYPE III 8-10 REPEATS OF FIBRONECTIN INDUCE AGGRECANASE ACTIVITY VIA ALPHA5BETA1 INTEGRIN AND THE TYPE III 13-14 REPEATS ACT VIA TLR 4 RECEPTORS

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Sofat, N, Troeberg, L, Nagase, H
التنسيق:	Journal article
منشور في:	2009

مواد مشابهة

The type III 8-10 repeats of fibronectin induce aggrecanase activity via alpha(5)beta(1) integrin and type III 13-14 repeats act via TLR 4 receptors
حسب: Sofat, N, وآخرون
منشور في: (2009)

Proteolytic fragments of fibronectin containing the type III-13 and III-14 repeats induce aggrecanase activity in cartilage
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In Vivo Functional Analysis of Drosophila Robo1 Fibronectin Type-III Repeats
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Cell adhesion and signaling on the fibronectin 1<sup>st</sup> type III repeat; requisite roles for cell surface proteoglycans and integrins
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Tenascin-C fragments induce aggrecanase activity in cartilage
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Fibronectin unfolding revisited: modeling cell traction-mediated unfolding of the tenth type-III repeat.
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Calcium pentosan polysulfate is a multi-functional aggrecanase inhibitor that enhances interaction with endogenous TIMP-3 in cartilage
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Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases.
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Aggrecanases in cartilage matrix breakdown
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Alternative splicing of the angiogenesis associated extra-domain B of fibronectin regulates the accessibility of the B-C loop of the type III repeat 8.
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Aggrecanases and cartilage matrix degradation.
حسب: Nagase, H, وآخرون
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Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity
حسب: Lo Cicero, A, وآخرون
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Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity.
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The eighth FIII domain of human fibronectin promotes integrin alpha5beta1 binding via stabilization of the ninth FIII domain.
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Fibronectin III 13-14 domains induce joint damage via Toll-like receptor 4 activation and synergize with interleukin-1 and tumour necrosis factor.
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Tenascin C promiscuously binds growth factors via its fifth fibronectin type III-like domain.
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Calcium pentosan polysulfate increases affinity between aggrecanases (ADAMTS-4 and-5) and TIMP-3 by a conformational change
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TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5).
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Elucidating the function of non catalytic domains of collagenases and aggrecanases
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Desumoylation of aggrecan and collagen II facilitates degradation via aggrecanases in IL-1β-mediated osteoarthritis
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Site-specific HNK-1 epitope on alternatively spliced fibronectin type-III repeats in tenascin-C promotes neurite outgrowth of hippocampal neurons through contactin-1.
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Aggrecanases and TIMP-3 in osteoarthritis: structure, function and in vivo challenges
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Isolation of fibronectin fragments that induce aggrecan degradation in cartilage
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Structure and functional significance of mechanically unfolded fibronectin type III1 intermediates.
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A Modified Fibronectin Type III Domain-Conjugated, Long-Acting Pan-Coronavirus Fusion Inhibitor with Extended Half-Life
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Normal spermatogenesis in Fank1 (fibronectin type 3 and ankyrin repeat domains 1) mutant mice
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Alterations in Fibronectin Type III Domain Containing 1 Protein Gene Are Associated with Hypertension.
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Fibronectin fragments induce aggrecan degradation in human cartilage and are increased in osteoarthritic cartilage
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Expression, refolding and spectroscopic characterization of fibronectin type III (FnIII)-homology domains derived from human fibronectin leucine rich transmembrane protein (FLRT)-1, -2, and -3
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C6: A Monoclonal Antibody Specific for a Fibronectin Epitope Situated at the Interface between the Oncofoetal Extra-Domain B and the Repeat III8.
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Clinical and molecular characteristics of 20 Chinese probands with Mucolipidosis type II and III alpha/beta
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The First Type III Domain of Fibronectin is Associated with the Expression of Cytokines within the Lung Tumor Microenvironment
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Fibronectin type III domain-containing 4 promotes the migration and differentiation of bovine skeletal muscle-derived satellite cells via focal adhesion kinase
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