First synthesis of 1-deazacytidine, the C-nucleoside analogue of cytidine

The synthesis of 1-deazacytidine, the C-nucleoside analogue of cytidine, is described. It involves coupling of a protected 2-amino-5-bromopyridine with perbenzylated ribonolactone and transformation of the pyridine ring into the desired substituted pyridone. This synthesis completes the family of C-...

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Bibliografski detalji
Glavni autori: Sollogoub, M, Fox, K, Powers, V, Brown, T
Format: Journal article
Jezik:English
Izdano: 2002