Co-producing human and animal experimental subjects: exploring the views of UK COVID-19 vaccine trial participants on animal testing

Preclinical (animal) testing and human testing of drugs and vaccines are rarely considered by social scientists side by side. Where this is done, it is typically for theoretically exploring the ethics of the two situations to compare relative treatment. In contrast, we empirically explore how human...

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المؤلفون الرئيسيون: Vanderslott, S, Palmer, A, Thomas, T, Greenhough, B, Stuart, A, Henry, JA, English, M, Naude, RDW, Patrick-Smith, M, Douglas, N, Moore, M, Hodgson, SH, Emary, KRW, Pollard, AJ
التنسيق: Journal article
اللغة:English
منشور في: SAGE Publications 2021
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author Vanderslott, S
Palmer, A
Thomas, T
Greenhough, B
Stuart, A
Henry, JA
English, M
Naude, RDW
Patrick-Smith, M
Douglas, N
Moore, M
Hodgson, SH
Emary, KRW
Pollard, AJ
author_facet Vanderslott, S
Palmer, A
Thomas, T
Greenhough, B
Stuart, A
Henry, JA
English, M
Naude, RDW
Patrick-Smith, M
Douglas, N
Moore, M
Hodgson, SH
Emary, KRW
Pollard, AJ
author_sort Vanderslott, S
collection OXFORD
description Preclinical (animal) testing and human testing of drugs and vaccines are rarely considered by social scientists side by side. Where this is done, it is typically for theoretically exploring the ethics of the two situations to compare relative treatment. In contrast, we empirically explore how human clinical trial participants understand the role of animal test subjects in vaccine development. Furthermore, social science research has only concentrated on broad public opinion and the views of patients about animal research, whereas we explore the views of a public group particularly implicated in pharmaceutical development: experimental subjects. We surveyed and interviewed COVID-19 vaccine trial participants in Oxford, UK, on their views about taking part in a vaccine trial and the role of animals in trials. We found that trial participants mirrored assumptions about legitimate reasons for animal testing embedded in regulation and provided insight into (i) the nuances of public opinion on animal research; (ii) the co-production of human and animal experimental subjects; (iii) how vaccine and medicine testing, and the motivations and demographics of clinical trial participants, change in an outbreak; and (iv) what public involvement can offer to science.
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spelling oxford-uuid:4e46e6df-3fd1-4e7f-b827-df76866c3d6e2023-10-13T11:54:37ZCo-producing human and animal experimental subjects: exploring the views of UK COVID-19 vaccine trial participants on animal testingJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4e46e6df-3fd1-4e7f-b827-df76866c3d6eEnglishSymplectic ElementsSAGE Publications2021Vanderslott, SPalmer, AThomas, TGreenhough, BStuart, AHenry, JAEnglish, MNaude, RDWPatrick-Smith, MDouglas, NMoore, MHodgson, SHEmary, KRWPollard, AJPreclinical (animal) testing and human testing of drugs and vaccines are rarely considered by social scientists side by side. Where this is done, it is typically for theoretically exploring the ethics of the two situations to compare relative treatment. In contrast, we empirically explore how human clinical trial participants understand the role of animal test subjects in vaccine development. Furthermore, social science research has only concentrated on broad public opinion and the views of patients about animal research, whereas we explore the views of a public group particularly implicated in pharmaceutical development: experimental subjects. We surveyed and interviewed COVID-19 vaccine trial participants in Oxford, UK, on their views about taking part in a vaccine trial and the role of animals in trials. We found that trial participants mirrored assumptions about legitimate reasons for animal testing embedded in regulation and provided insight into (i) the nuances of public opinion on animal research; (ii) the co-production of human and animal experimental subjects; (iii) how vaccine and medicine testing, and the motivations and demographics of clinical trial participants, change in an outbreak; and (iv) what public involvement can offer to science.
spellingShingle Vanderslott, S
Palmer, A
Thomas, T
Greenhough, B
Stuart, A
Henry, JA
English, M
Naude, RDW
Patrick-Smith, M
Douglas, N
Moore, M
Hodgson, SH
Emary, KRW
Pollard, AJ
Co-producing human and animal experimental subjects: exploring the views of UK COVID-19 vaccine trial participants on animal testing
title Co-producing human and animal experimental subjects: exploring the views of UK COVID-19 vaccine trial participants on animal testing
title_full Co-producing human and animal experimental subjects: exploring the views of UK COVID-19 vaccine trial participants on animal testing
title_fullStr Co-producing human and animal experimental subjects: exploring the views of UK COVID-19 vaccine trial participants on animal testing
title_full_unstemmed Co-producing human and animal experimental subjects: exploring the views of UK COVID-19 vaccine trial participants on animal testing
title_short Co-producing human and animal experimental subjects: exploring the views of UK COVID-19 vaccine trial participants on animal testing
title_sort co producing human and animal experimental subjects exploring the views of uk covid 19 vaccine trial participants on animal testing
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