Transcriptomic signatures induced by the Ebola virus vaccine rVSVΔG-ZEBOV-GP in adult cohorts in Europe, Africa, and North America: a molecular biomarker study

Transcriptomic signatures induced by the Ebola virus vaccine rVSVΔG-ZEBOV-GP in adult cohorts in Europe, Africa, and North America: a molecular biomarker study

Background A recombinant vesicular stomatitis virus vector expressing the Zaire Ebola virus glycoprotein (rVSVΔG-ZEBOV-GP) vaccine has been reported as safe, immunogenic, and highly protective in a ring vaccination trial. We aimed to identify transcriptomic immune response biomarker signatures induc...

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Main Authors: Vianello, E, Gonzalez-Dias, P, van Veen, S, Engele, CG, Quinten, E, Monath, TP, Medaglini, D, Agnandij, ST, Ahmed, R, Anderson, J, Auderset, F, Bejon, P, Borgianni, L, Brosnahan, J, Ciabattini, A, Engler, O, Haks, MC, Harandi, AM, Heppner, DG, Gerlini, A, Huttner, A, Kremsner, PG, Ndungu, FM, Njuguna, P, Ottenhoff, THM, Pejoski, D, Page, M, Pozzi, G, Santoro, F, Siegrist, CA, Dubey, S, Eichberg, M, Ndong, EP, Lumeka, K, Nakaya, HI, Gonzales Dias Carvalho, P, Rothenberger, S, Nakka, SS, Essone, PN, Agnandji, ST
Format: Journal article
Jezik:English
Izdano: Elsevier 2021

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