Resolving apparent conflicts between theoretical and experimental models of phosphate monoester hydrolysis

Understanding phosphoryl and sulfuryl transfer is central to many biochemical processes. However, despite decades of experimental and computational studies, a consensus concerning the precise mechanistic details of these reactions has yet to be reached. In this work we perform a detailed comparative...

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Main Authors: Duarte, F, Åqvist, J, Williams, N, Kamerlin, S
Format: Journal article
Jezik:English
Izdano: American Chemical Society 2014