Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis.

Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis.

CONTEXT: Mutations in the low-density lipoprotein receptor-related protein 5 (LRP5) gene cause rare syndromes characterized by altered bone mineral density (BMD). More common LRP5 variants may affect osteoporosis risk in the general population. OBJECTIVE: To generate large-scale evidence on whether...

Bibliografski detalji
Glavni autori:	van Meurs, J, Trikalinos, T, Ralston, S, Balcells, S, Brandi, M, Brixen, K, Kiel, D, Langdahl, B, Lips, P, Ljunggren, O, Lorenc, R, Obermayer-Pietsch, B, Ohlsson, C, Pettersson, U, Reid, D, Rousseau, F, Scollen, S, Van Hul, W, Agueda, L, Akesson, K, Benevolenskaya, L, Ferrari, S, Hallmans, G, Hofman, A, Husted, L
Format:	Journal article
Jezik:	English
Izdano:	2008

Slični predmeti

Influence of LRP5 polymorphisms on normal variation in BMD.
od: Koay, M, i dr.
Izdano: (2004)

Evolutionary and functional analyses of LRP5 in archaic and extant modern humans
od: Neus Roca-Ayats, i dr.
Izdano: (2024-05-01)

Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition.
od: Ryan C Riddle, i dr.
Izdano: (2013-01-01)

LRP10 in α-synucleinopathies
od: Guerreiro, R, i dr.
Izdano: (2018)

Dissecting molecular differences between Wnt coreceptors LRP5 and LRP6.
od: Bryan T MacDonald, i dr.
Izdano: (2011-01-01)

Association between TGF-beta and LRP 5 and 6 genetic polymorphisms with fracture risk and bone mineral density in the EPOS study
od: Kaptoge, S, i dr.
Izdano: (2006)

LRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin.
od: John J Young, i dr.
Izdano: (2007-03-01)

sLRP1ng Up Glucose: LRP1 Regulates Hepatic Insulin Responses
od: Stephen D. Lee, i dr.
Izdano: (2016-05-01)

eys+/-; lrp5+/− Zebrafish Reveals Lrp5 Can Be the Receptor of Retinol in the Visual Cycle
od: Shimpei Takita, i dr.
Izdano: (2020-12-01)

LRP-dependent and -independent internalisation of TIMP-3
od: Scilabra, S, i dr.
Izdano: (2011)

Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.
od: Martin F Dietrich, i dr.
Izdano: (2010-04-01)

The Relationship Between LRP-5 and LRP-6 Gene Mutations and Postmenopausal Type 2 Diabetes and Obesity
od: Jun Li, i dr.
Izdano: (2025-01-01)

Balancing WNT signalling in early forebrain development: The role of LRP4 as a modulator of LRP6 function
od: Shuang Geng, i dr.
Izdano: (2023-04-01)

LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer’s disease
od: Carlos eSpuch, i dr.
Izdano: (2012-07-01)

Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts.
od: Aimy Sebastian, i dr.
Izdano: (2017-01-01)

Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study.
od: Langdahl, B, i dr.
Izdano: (2008)

Assessment of genes LRP5, BVP4, TGF^l polymorphisms significance in postmenopausal osteoporosis
od: KA Myakotkin, i dr.
Izdano: (2008-06-01)

Bone mass, structure and turnover in EOOP patients with LRP5/LRP6 mutations - Case series of 33 patients
od: Julian Stürznickel, i dr.
Izdano: (2020-10-01)

BinR-LRP: A divide and conquer heuristic for large scale LRP with integrated microscopic agent-based transport simulation
od: Elija Deineko, i dr.
Izdano: (2024-03-01)

P228: Molecular and clinical analyses of LRP1 and LRP2 variants in human congenital cardiac left-sided lesions
od: Xin Chen, i dr.
Izdano: (2024-01-01)

Dkk1 stabilizes Wnt co-receptor LRP6: implication for Wnt ligand-induced LRP6 down-regulation.
od: Yonghe Li, i dr.
Izdano: (2010-06-01)

Ubiquitin-dependent folding of the Wnt signaling coreceptor LRP6
od: Elsa Perrody, i dr.
Izdano: (2016-10-01)

The extraction of LRP via functional data analysis techniques.
od: Zhao, Y, i dr.
Izdano: (2012)

Multi-faceted role of LRP1 in the immune system
od: Olga Sizova, i dr.
Izdano: (2023-03-01)

The apolipoprotein receptor LRP3 compromises APP levels
od: Inmaculada Cuchillo-Ibañez, i dr.
Izdano: (2021-11-01)

Common arterial trunk and ventricular non-compaction in Lrp2 knockout mice indicate a crucial role of LRP2 in cardiac development
od: Maria E. Baardman, i dr.
Izdano: (2016-04-01)

Inhibition of LRP1 shedding reverses cartilage matrix degradation in osteoarthritis
od: Yamamoto, K, i dr.
Izdano: (2017)

Binding of alpha2ML1 to the low density lipoprotein receptor-related protein 1 (LRP1) reveals a new role for LRP1 in the human epidermis.
od: Marie-Florence Galliano, i dr.
Izdano: (2008-07-01)

Wise regulates bone deposition through genetic interactions with Lrp5.
od: Debra L Ellies, i dr.
Izdano: (2014-01-01)

The fusion gene LRP1–SNRNP25 drives invasion and migration by activating the pJNK/37LRP/MMP2 signaling pathway in osteosarcoma
od: Peipei Xing, i dr.
Izdano: (2024-04-01)

Synapse-specific Lrp4 mRNA enrichment requires Lrp4/MuSK signaling, muscle activity and Wnt non-canonical pathway
od: Hongyang Jing, i dr.
Izdano: (2021-06-01)

Critical Endothelial Regulation by LRP5 during Retinal Vascular Development.
od: Wei Huang, i dr.
Izdano: (2016-01-01)

Apoer2/Lrp8: the undercover cop of synaptic homeostasis
od: Gordon C Werthmann, i dr.
Izdano: (2024-01-01)

416 LRP1 as a modulator of hippocampal neurogenesis and neurodegeneration
od: Kristi Dietert, i dr.
Izdano: (2022-04-01)

LRP6-mediated phosphorylation of connexin43 in myocardial infarction
od: Xu-min Zhang, i dr.
Izdano: (2023-03-01)

LRP12 is an endogenous transmembrane inactivator of α4 integrins
od: MengWen Huang, i dr.
Izdano: (2023-06-01)

Resolving the incompatibility between SET-LRP and non-disproportionating solvents
od: Nabil Bensabeh, i dr.
Izdano: (2023-08-01)

Expression of LRP8 in gastric cancer and its significance in tumorigenesis
od: LIU Bin , ZHENG Pengyuan , MI Yang , REN Feifei , GAO Shuang , LIU Chuan , LI Fazhan
Izdano: (2021-04-01)

Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4
od: Andrea M Gomez, i dr.
Izdano: (2014-11-01)

Lrp, a global regulator, regulates the virulence of Vibrio vulnificus
od: Yu-Chi Ho, i dr.
Izdano: (2017-08-01)