Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei.

The metaphase-anaphase transition is orchestrated through proteolysis of numerous proteins by a ubiquitin protein ligase called the anaphase-promoting complex or cyclosome (APC/C). A crucial aspect of this process is sister chromatid separation, which is thought to be mediated by separase, a thiol p...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Oliveira, R, Hamilton, R, Pauli, A, Davis, I, Nasmyth, K
Format: Journal article
Sprog:English
Udgivet: 2010

Lignende værker