Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei.

Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei.

The metaphase-anaphase transition is orchestrated through proteolysis of numerous proteins by a ubiquitin protein ligase called the anaphase-promoting complex or cyclosome (APC/C). A crucial aspect of this process is sister chromatid separation, which is thought to be mediated by separase, a thiol p...

Полное описание

Библиографические подробности
Главные авторы:	Oliveira, R, Hamilton, R, Pauli, A, Davis, I, Nasmyth, K
Формат:	Journal article
Язык:	English
Опубликовано:	2010

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