HLA-A*0201, HLA-A*1101, and HLA-B*0702 transgenic mice recognize numerous poxvirus determinants from a wide variety of viral gene products.

HLA-A*0201, HLA-A*1101, and HLA-B*0702 transgenic mice recognize numerous poxvirus determinants from a wide variety of viral gene products.

In virus models explored in detail in mice, CTL typically focus on a few immunodominant determinants. In this study we use a multipronged approach to understand the diversity of CTL responses to vaccinia virus, a prototypic poxvirus with a genome approximately 20-fold larger than that of the model R...

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Bibliographic Details
Main Authors: Pasquetto, V, Bui, H, Giannino, R, Banh, C, Mirza, F, Sidney, J, Oseroff, C, Tscharke, D, Irvine, K, Bennink, JR, Peters, B, Southwood, S, Cerundolo, V, Grey, H, Yewdell, J, Sette, A
Format: Journal article
Language:English
Published: 2005

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