Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age.
BACKGROUND: Plasmodium falciparum malaria is a pressing global health problem. A previous study of the malaria vaccine RTS,S (which targets the circumsporozoite protein), given with an adjuvant system (AS02A), showed a 30% rate of protection against clinical malaria in children 1 to 4 years of age....
Main Authors: | Bejon, P, Lusingu, J, Olotu, A, Leach, A, Lievens, M, Vekemans, J, Mshamu, S, Lang, T, Gould, J, Dubois, M, Demoitié, M, Stallaert, J, Vansadia, P, Carter, T, Njuguna, P, Awuondo, K, Malabeja, A, Abdul, O, Gesase, S, Mturi, N, Drakeley, C, Savarese, B, Villafana, T, Ballou, W, Cohen, J |
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Format: | Journal article |
Language: | English |
Published: |
2008
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