Site-selective chemoenzymatic construction of synthetic glycoproteins using endoglycosidases
Combined chemical tagging followed by Endo-A catalysed elongation allows access to homogeneous, elaborated glycoproteins. A survey of different linkages and sugars demonstrated not only that unnatural linkages can be tolerated but they can provide insight into the scope of Endo-A transglycosylation...
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Bibliographic Details
Main Authors: |
Fernandez-Gonzalez, M,
Boutureira, O,
Bernardes, G,
Chalker, J,
Young, M,
Errey, J,
Davis, B |
Format: | Journal article
|
Language: | English |
Published: |
2010
|